The 2017 Nobel Prize in Physiology or Medicine was awarded to American scientists Jeffrey C. Hall, Michael Rosbash and Michael W. Young for their "discoveries related to the molecular mechanism of the circadian clock."
Simply put, the most valuable interpretation of this study for people with diabetes is that they should work and rest on a regular basis.
Biological clock disorders can indeed lead to endocrine and metabolic diseases such as diabetes. So how does the biological clock affect blood sugar? How to use the biological clock to scientifically stabilize blood sugar levels?
1Rhythm disorders can cause blood sugar fluctuations
Everyone has their own adaptive and long-term stable routine. Once this rhythm is disrupted, the biological clock of hormone secretion will be disrupted. Some hormones that cause blood sugar to rise (cortisol, etc.) may be secreted more, causing blood sugar levels to rise.
On the other hand, staying awake or even excited during a period when you should normally be asleep will definitely require more energy replenishment. If you fail to replenish energy in time, it may lead to hypoglycemia; conversely, if you accidentally eat too much, your blood sugar will rise. After all, the temptation of "late night dining halls" is too great.
2Poor sleep quality can lead to elevated blood sugar
This does not mean that you must go to bed early and get up early. A biological clock that is truly beneficial to health only needs to meet two points: first, regularity, and second, sleep well. Insufficient effective sleep time will disrupt the body's biological clock. In order to maintain normal blood sugar, the body will work hard to release more insulin. In the long run, the body's insulin sensitivity decreases, and blood sugar naturally rises.
3How to improve sleep quality?
First of all, people with diabetes should limit their sleep time during the day. Except for the elderly who can take a nap during the day, they should try to avoid sleeping during the day.
Secondly, moderate exercise can increase the time of deep sleep and improve sleep quality, but it is not advisable to perform strenuous exercise before going to bed.
Finally, obese people are more likely to have sleep disorders, such as sleep apnea due to severe snoring. Therefore, weight loss is also one of the necessary tasks on the road to controlling sugar.
The country's first SGLT2 inhibitor Andatan (dapagliflozin) takes into account the needs of these two aspects.
On the one hand, dapagliflozin relies on a new, non-insulin-dependent mechanism of action to highly selectively inhibit sodium-glucose co-transporter 2 (SGLT2), reducing renal glucose reabsorption and directly excreting excess sugar through urine, thus Reduces blood sugar levels in people with type 2 diabetes to treat diabetes.
On the other hand, results such as weight loss and blood pressure reduction were also found in clinical studies of dapagliflozin.
*The above content is for reference only. Please adjust your sleep reasonably according to your actual situation and take medication under the guidance of a doctor.
